
MOTS-c
99% Pure | USA Made | Multi Dose
MOTS-c is a mitochondria-derived peptide that regulates metabolic homeostasis, supports exercise capacity, and promotes healthy aging at the cellular level.
Dosage
$219.00
Pairs well with
Bacteriostatic Water
Required for reconstitution
$12.00
Note: Peptides are not ready to use. Must purchase BAC water for reconstitution.
What makes MOTS-c exceptional
Every treatment in our catalog is physician-reviewed and pharmacy-compounded. Here's why MOTS-c stands out.
First peptide to demonstrate mitochondria-to-nucleus retrograde signaling
What is MOTS-c?
MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA type-c) is a recently discovered peptide encoded within the mitochondrial genome. It acts as a cellular energy regulator, activating the AMPK pathway to optimize glucose metabolism, enhance exercise capacity, and promote metabolic flexibility.

10mg weekly · Subcutaneous injection
Administered under physician guidance
Why choose MOTS-c?
MOTS-c targets aging at its root — mitochondrial function. Patients choose it for:
Enhanced exercise performance and endurance capacity
Improved insulin sensitivity and glucose utilization
Cellular-level anti-aging through mitochondrial optimization
Fat metabolism enhancement via AMPK pathway activation
Protection against age-related metabolic decline

What sets MOTS-c apart
MOTS-c is the first mitochondria-derived peptide shown to regulate nuclear gene expression — a breakthrough concept called ‘retrograde signaling.’ It literally allows your mitochondria to communicate with and reprogram your cell nuclei for better metabolic function.
Backed by research
Peer-reviewed studies supporting MOTS-c treatment protocols.
MOTS-c and Exercise Endurance in Aging
MOTS-c treatment improved physical capacity and reversed age-dependent insulin resistance in models.
Pairs well with
Complementary treatments often used alongside MOTS-c.
Ready to start your treatment?
All orders require physician approval. You're only charged if approved.
